T cells go universal
نویسندگان
چکیده
منابع مشابه
T Helper Cells Profile and CD4+CD25+Foxp3+Regulatory T Cells in Polycystic Ovary Syndrome
Background: Polycystic ovary syndrome (PCOS) is considered as the most common cause of female infertility that affects 4-10% of women in the reproductive age. Previous studies have shown the role of a balanced immune response in a successful pregnancy and fertility. Objective: To investigate the T helper cells type 1 (Th1) /Th2/Th17/Treg paradigms in peripheral blood of infertile PCOS compared ...
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One of the essential protection mechanisms of immune system is Treg cells which play an important role in maintenance ofimmune homeostasis. However, they may also inhibit immune functions against tumor cells. It has been reported that Treg cellsare increased in patients suffering from different types of cancer. Increased number of Treg cells has been shown in tumor lymphnodes, peripheral blood,...
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Background: Adipose derived stem cells (ASCs) provoke the accumulation and expansion of regulatory T cells, leading to the modulation of immune responses in tumor microenvironment. Objective: To assess the effect of tumoral ASCs on the trend of regulatory T cells differentiation. Methods: Peripheral blood naïve CD4+ T cells were co-cultured with ASCs derived from breast cancer or normal breast ...
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Endothelial-to-mesenchymal transition (EndMT) is a poorly understood phenomenon that leads to endothelial cells acquiring a variety of different mesenchymal fates. This results in a number of pathological consequences of considerable clinical significance in diseases ranging from cavernous malformations in the brain to tissue fibrosis, atherosclerosis, and cancer. Importantly, while there appea...
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muscle dystrophin expression (Gussoni et al., 1999). The Our limited life expectancy, and inevitable death, is origin of the adult stem cells is not known. They may be brought about by the ongoing deterioration of the body’s residual undifferentiated embryonic cells or, as recent essential cell types, tissues, and organs. Thus, either a evidence suggests, committed/differentiated adult cells re...
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ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2013
ISSN: 1945-3477
DOI: 10.1038/scibx.2013.1337